Insidensi dan Derajat Keparahan MIS-C Pasca Vaksinasi COVID-19

Oleh :

dr. Nurul Falah

Bagaimana sesungguhnya insidensi dan derajat keparahan MIS-C pasca vaksinasi COVID-19? Saat ini belum diketahui bahwa pemberian vaksin COVID-19 berhubungan dengan multisystem inflammatory syndrome in children (MIS-C), tetapi terdapat laporan kejadian multisystem Inflammatory Syndrome in Adults (MIS-A) pasca vaksinasi COVID-19.[1-3]

Vaksinasi COVID-19 telah menjadi metode yang efektif dalam menurunkan risiko COVID-19. Meskipun tidak 100% melindungi diri dari virus SARS-CoV-2, sejumlah studi telah melaporkan keberhasilan vaksinasi COVID-19 dalam menurunkan morbiditas dan mortalitas akibat COVID-19 secara global, termasuk pada populasi anak.[1-3]

Dengan semakin luasnya pemberian vaksin COVID-19 pada populasi anak, maka dibutuhkan informasi bagaimana sesungguhnya pengaruh vaksinasi COVID-19 terhadap MIS-C? Apakah ada kejadian MIS-C pasca vaksinasi COVID-19? Lalu, apakah ada rekomendasi untuk pasien pasca MIS-C yang ingin mendapatkan vaksinasi COVID-19?

(Konten ini khusus untuk dokter. Registrasi untuk baca selengkapnya)

Referensi

1. Maltezou HC, Panagopoulos P, Sourri F, et al. COVID-19 vaccination significantly reduces morbidity and absenteeism among healthcare personnel: A prospective multicenter study. Vaccine. 2021;39(48):7021-7.
2. Tiwari A, Balan S, Rauf A, et al. COVID-19 related multisystem inflammatory syndrome in children (MIS-C): a hospital-based prospective cohort study from Kerala, India. BMJ Paediatr Open. 2021;5(1):e001195.
3. Wisniewski M, Chun A, Volpi S, et al. Outcomes After SARS-CoV-2 Vaccination Among Children With a History of Multisystem Inflammatory Syndrome. JAMA Netw Open. 2022;5(3):e224750.
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12. Yousaf AR, Cortese MM, Taylor AW. Reported cases of multisystem inflammatory syndrome in children (MIS-C) aged 12–20 years in the United States who received COVID-19 vaccine, December 2020 through August 2021. medRxiv 2022.